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Angelo's Bio-manufacturing "Breakthrough" Practice

Date：Mar 27,2026

Author：安各洛公司

First article  Next article

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Zhejiang Dalian Jianchang team constructed a complete biosynthesis pathway of sanguinarine and its derivatives engineered strains integrated temperature control module titer exceeding 448mgL

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Jun 20,2024
The MIT team developed an amber polymer to preserve DNA which can be stored at room temperature and has set up a company to convert it

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Jun 17,2024
The team identified new targets for tolerating furfural and acetic acid in liapolytic yeast at the whole genome level and efficiently utilized lignocellulosic hydrolysate to promote green bio-manufacturing

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Jun 13,2024
The latest review by Chen Zhen team of Tsinghua University: Important progress has been made in microbial synthesis of diols and 3 types of specific biod diols have been commercially produced

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Jun 03,2024
Yuan Yingjin team: Through advanced engineering strategies to achieve efficient conversion of lignin to highly homogeneous PHA

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May 30,2024
Using microbial fermentation to convert CO₂ into fat the Wyss Institute spin-off company has received more than $8 million in financing and its first product is about to hit the market

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May 16,2024
Jay Keasling's team fully biosynthesizes QS-21 in engineered yeast making it more economical to produce potent adjuvants and reduce vaccine costs

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May 09,2024
The latest review by Chen Guoqiang's team: Extremophiles are expected to become the "next generation" cell factories that can be used to produce a variety of high-value compounds

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Apr 29,2024
With a focus on alternative proteins the Bezos Earth Foundation launched the "AI Climate and Nature" Challenge with $100 million

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Apr 28,2024
Motif Neurotech which develops brain-computer interfaces that only need to penetrate the skull has completed human testing and published papers

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Apr 21,2024
2024 Top 10 trends in the synthetic biology industry track: Gene therapy is far ahead and alternative proteins have great potential

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Apr 02,2024
The Chinese human complex DNA methylation clock created by Beijing Genomics Institute provides a new perspective for understanding the epigenetic mechanisms of aging

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Apr 01,2024
The Stanford team has proposed a new anti-aging therapy that restores the "youthful state" of the immune system in mice with a single injection and the effect is significant

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Mar 28,2024
"Nature" : Stress makes people depressed the real reason has been found! A new target for depression treatment is expected

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Mar 25,2024
World first! A gene-edited pig kidney was transplanted into a living human for the first time and the patient's condition continued to improve without rejection

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Mar 22,2024
Anti-aging company Altos Labs published Cell paper: Ancient retrovirus invasion played a key role in brain evolution

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Mar 11,2024
Scientists have uncovered the mystery of the intestinal complement system opening new directions for the study of the immune system's complement and promoting the prevention and treatment of intestinal diseases

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Mar 10,2024
With a production of 25mgL the team of China Pharmaceutical University clarified a new biosynthetic pathway of hypericin which can be used to produce multiple 3-O-galactosides

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Mar 07,2024
The Peking University team elucidates the molecular mechanism of macrophage aging and will enhance type II immune signaling for anti-aging therapy

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Mar 03,2024
The world's first research on the fermentation of lactic acid with "chemical synthetic sugar" as the only substrate is expected to solve the problem of biomass sugar supply and food competition

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Feb 28,2024
Supported by Bezos and Wuxi Apptec the anti-aging company is using senolytic drugs to treat diabetic macular edema and achieve lasting vision improvement with one injection

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Feb 27,2024
Photoelectric bioregulation in a major advance: Scientists pacing adult live pig hearts are about 25 times more efficient than the previous generation of materials

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Feb 22,2024
The South China Normal University team developed a new display technology that can achieve both reflection and transmission and the process can be standardized

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Feb 02,2024
The synthesis of α-terpenol by the modularized Rhodospora rhodospora yeast in Dalian Chemical Institute with the most efficient price of 1.5mgL is used in flavor and pharmaceutical industry

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Jan 22,2024
Naringenin titers increased by more than 10 times and the University of Groningen team built an engineered Penicillium Rubens cell factory which has the potential for large-scale production

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Jan 19,2024
Scientists have successfully manipulated arbitrary nanostructures to convert infrared images into visible light which can be used in fields such as night vision technology and medical testing

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Jan 01,2024
The European Pathfinder Challenge project to transform hydrogen-oxidizing bacteria to produce proteins was funded by $6 million and promoted by four institutions including Ginkgo subsidiaries

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Dec 20,2023
Scientists have confirmed a new mechanism by which cancer syntheses to death successfully validated in 488 tumor cell lines and have set up a company to develop new drugs

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Dec 20,2023
华工团队提出利用多价抗体改造细胞，有望用于治疗炎症性肠病和急性肾损伤

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Dec 13,2023
Fudan scholars proposed a new protein analysis algorithm to bring timely supplement to the cryo-electron microscope toolbox and the relevant code has been open source on GitHub

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Dec 04,2023
Ergothioneine not just antioxidant!

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Nov 09,2023
Synthetic biological plant cell culture: a large unmet market space

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Nov 07,2023
CELL | Brain Science research team of Shenzhen University of Science and Technology/Shenzhen Advanced Institute of Chinese Academy of Sciences proposed a novel neuroregulatory therapy for Parkinson's disease

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Nov 05,2023
The Zhejiang Institute of Technology team accurately constructs two-dimensional nanomaterials with different crystal nuclei which can be used as drug delivery carriers

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Nov 02,2023
Efficient biosynthesis of p-coumaric acid by Corynebacterium glutamicum

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Oct 26,2023
The Round Table Forum on "Challenges and Prospects of Exocrine Body Industrialization" of Baiaogu&Enze Kangtai Successfully Ends

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Oct 26,2023
Multiple pharmaceutical companies have gathered technical backbone and CMC process technology has long been known Bio ONE is about to open!

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Oct 26,2023
Interview | Nature Paper on Returning to Hometown as a Civil Servant: New Breakthrough in Polymer Material Interface Research

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Oct 25,2021
BioPark Hotspot | Academician Zhang Dan Attends the 50th Anniversary Celebration of the American Cancer Foundation and Meets with the Current President of the National Cancer Institute

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Oct 25,2023
Scientists have cracked the longevity gene of the "immortal beast" and successfully migrated it to house mice extending their lifespan by about 4.4%

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Oct 25,2023
Scientists develop spatial tranomics technology to construct a spatiotemporal tranome spectrum of 3D mouse embryos

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Oct 25,2023
BioNTech's new CAR-T hope for solid tumor cure?

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Oct 24,2023
How can synthetic biotechnology be applied in the field of bulk chemical engineering d on the thinking of Kaisai Biology?

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Oct 24,2023
More in love with the First Third Party? Mercado returns to Kolenbotai preclinical ADC

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Oct 23,2023
Multi pathway optimization strategy for efficient production of 2 '- fucosyllactose by engineered Escherichia coli C41 (DE3)

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Oct 23,2023
DeepTech Releases a Research Report on "Frontier Technologies Empowering New Drug Development - Artificial Intelligence | Synthetic Biology | Gene Delivery Technology | Organ and Organ Chips"

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Oct 22,2023
Why is the listed company Kaisai Biotechnology located in the 17000 acre Shanxi Synthetic Biology Industrial Park

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Oct 19,2023
Synthetic biology is still in its very early stages and is still being explored. "Interview with Liu Chenli from Shenzhen Advanced Institute

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Oct 18,2023
Roche pays another 2 billion dollars! Multiple candidate drugs for molecular glue have been obtained and new data shows that they can effectively reduce tumor size

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Oct 18,2023
Baiaogu & Enzekangtai | "Challenges and Prospects of Exosome Industrialization" roundtable discussion will be held grandly tomorrow...

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Oct 18,2023
Scientists have designed a new method for protein aggregation using disulfide bond reducing agents to break down folded proteins which can be used to generate multifunctional protein coatings

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Oct 17,2023
The latest review by the Shenzhen Bay Laboratory team: The "divide and conquer" strategy in protein structure prediction and the post AlphaFold2 era

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Oct 17,2023
Interview with Academician Sui Senfang: Analyzing the in situ structure of super large protein complexes to achieve the highest resolution of cell slice samples

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Oct 13,2023
Belgian biotech company raised $100 million in round C financing supported by Pfizer and ALK-5 inhibitors have started Phase IIa clinical trials

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Oct 12,2023
The team from Tianjin Institute of Industrial Biology uses carbon dioxide to synthesize edible sugar with a carbon conversion rate of over 80% providing an important route reference for artificial biological sugar production

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Oct 10,2023
The Suda team has developed an integrated electrode with a Faraday efficiency of nearly 100% for carbon monoxide which is expected to achieve the utilization of carbon dioxide resources

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Oct 09,2023
In-depth research on strategic brand positioning and leading the nutritional food market

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Oct 09,2023

Company News

Angelo's Bio-manufacturing "Breakthrough" Practice

Perception of bleeding in-situ gelation! This intelligent "living glue" enables precise treatment of inflammatory bowel disease

"Extremely Selfish" Parasite: The Smallest Archaea Challenging the Definition of Life Discovered in the Ocean

CCTV Documentary "How Life Affects Life" | Do We Have Ways to Deal with Superbug Infections?

When Cells Learn to "Open the Door and Welcome Guests": How Do ABC Transporters Deliver Non-Natural Amino Acids?

How did the earliest life "encapsulate" itself?

Producing Antibodies Using mRNA

Four New Perspectives on PD-1 Therapy

The Power of AI in Drug Development: Advancing to Phase III Clinical Trials in Just 4 Years

Allogeneic CD19 CAR-T cells combined with IL-2 significantly improve clinical activity.

In vivo studies involve not only CAR-T cells but also TCR-T cells.

Arrowhead joins the battlefield with a new RNAi approval.

From 0 to 1! Fosun Pharma's POHERDY® is approved by the FDA to become the first biosimilar of pertuzumab in the United States.

In vivo CAR-T: EDV+AAV dual vectors - precise insertion of CAR at specific sites.

A Phase II trial of the PD-1×CTLA-4 bispecific antibody has failed.

After the failure of the Phase III clinical trial the shareholders plan to buy the company.

Sdance: Solid Tumor CAR-T Going Global!

Sana halts the development of allogeneic CAR-T.

Intellia's in vivo CRISPR: A patient died after experiencing grade 4 hepatotoxicity.

The American Caribou addresses the persistence of universal CAR-T.

The NREL team in the United States has achieved a green upgrade of polystyrene with a hybrid process producing adipic acid and reducing emissions by 61%.

Nature highlights that ETH Zurich has "hijacked" bacterial transport proteins to achieve efficient delivery of non-natural amino acids.

A lab-grown meat company has gone bankrupt and its scientific research results will be shared. The Good Food Institute (GFI) is collaborating with Tufts University to create a shared cell bank platform.

The Zhejiang University of Technology team has reengineered Pseudomonas to achieve efficient production of green surfactants.

DeepMind collaborates with Yale to crack the cancer immunotherapy puzzle with AI models successfully identifying key drugs to turn "cold tumors" into "hot tumors."

A decade of protein design leapfrog: David Baker discusses the scientific future of "designing proteins from scratch."

Beijing University of Chemical Technology has developed a halophilic bacterial "plastic-making" platform to achieve efficient synthesis of P34HB.

With technology originating from Harvard and led by the former CEO of Oatly this startup is reshaping the protein industry.

A South Korean team has constructed an end-to-end microbial system to achieve efficient synthesis of 100% bio-d long-chain polyesters.

Sustainable proteins embrace policy tailwinds: GFI's leader discusses industry reshaping and future pathways.

Effective even in the dark! Scientists unveil the "natural battery" in soil paving a new way for pollution control.

Supporting "Healthy Shanghai 2030" Novartis has proposed a "digital blueprint" for lipid management and cardiovascular prevention.

A team from Auburn University has engineered Bacillus subtilis to achieve efficient synthesis of D-23-butanediol.

A team from the University of Washington has developed a biomimetic coating that significantly enhances the performance of green composite materials.

The 2025 Nobel Prize in Chemistry has been announced awarded for research related to l-organic works.

Jiangnan University integrates bolic engineering with genetic encoding to create an efficient artificial enzyme design platform.

Unveiling the "safety valve" of the immune system three scientists are awarded the 2025 Nobel Prize in Physiology or Medicine.

AI-modified proteins can bypass detection. Microsoft collaborates with tech companies to patch DNA synthesis screening.

A Belgian team has drawn up a blueprint for engineering "non-model bacteria" ushering in a new era of precision bio-manufacturing.

A Brazilian team has developed a refining route to efficiently extract high-value chemicals from the aqueous phase of bio-oil.

A team from Monash University has developed a phage cocktail therapy to precisely target drug-resistant Enterobacter cloacae.

A UK startup has acquired a bankrupt factory gaining a fermentation capacity of millions of liters.

A team from the Chinese Academy of Sciences has identified and characterized the key enzyme for Reb M synthesis breaking through the bottleneck in yield.

Oobli's third sweet protein has received FDA GRAS certification entering the food and beverage market.

A UK company has pioneered a fully biodegradable reflective pigment which is expected to be commercially available by 2026.

Zhejiang University of Technology's new review: Metabolic engineering optimizes microbial chassis to promote the industrialization of D-panthenol.

A South Korean team has developed a CRISPRa/i system for dual - mode gene regulation to boost the production of violacein.

The team from Shanghai Jiao Tong University has driven enzyme evolution using AI resulting in a 1000 - fold increase in the production of succinic acid.

Bill Gates and Novo Nordisk have invested another $26 million to explore the synthesis of proteins from carbon dioxide.

A Dutch startup has completed a $35 million financing round to accelerate the commercialization of fungal protein.

Backed by Bill Gates a Singaporean startup has secured $3.1 million in funding to transform waste into a palm oil alternative.

Tianjin University of Science and Technology has bolically engineered Escherichia coli to achieve efficient production of N - acetylneuraminic acid.

Colossal is advancing the de-extinction of the dodo: breeding the world's first pigeon reproductive cells and securing another $120 million in funding.

The team from Tianjin University has engineered the modification of Bacillus amyloliquefaciens to efficiently synthesize iturin A.

Stanford University and the Arc Institute have collaborated and AI has successfully generated functional phage genomes to combat antibiotic resistance.

Tianjin Institute of Industrial Biotechnology and other institutions have engineered the modification of maltose enzyme to achieve efficient conversion of α-glucan.

Using precision fermentation to turn waste into treasure a German biotech startup has completed a $19 million financing round to build a future free of microplastics.

Canada bets on future proteins with startups joining forces to develop mycelium-d proteins.

Jiangnan University has engineered E. coli to efficiently synthesize 6′-sialyllactose.

Incubated by the University of Cambridge the startup has raised 100 million yuan in initial funding to develop plant-d materials to end the “plastic dilemma.”

A research team from Zhejiang University of Technology has modified E. coli to achieve efficient production of Vitamin B5.

The Second Act for Synthetic Biology Star Amyris: Focus Collaboration and Profitability

The patent dispute over animal-free "ovalbumin" has escalated with a lawsuit filed in court.

AI-driven protein design is entering the "programmable" era with a Harvard team proposing a suite of seven tools to streamline the entire process.

The U.S. FDA plans to eliminate the "self-determination of safety" pathway which may impact the food technology industry.

The team from Beijing Forestry University has developed a green catalytic technology to transform soapberry "waste" into prebiotics.

With a daily throughput exceeding 14 Tb BGI Genomics has launched the ultra-high-throughput sequencer T7+.

The team from Kobe University has reengineered Escherichia coli to achieve highly efficient synthesis of 25-pyridinedicarboxylic acid (25-PDCA) with a yield increase of more than seven times.

Shandong University transforms the highly active β-glucosidase of Trichoderma reesei promoting the economical production of lignocellulosic sugars.

A Dutch company has scaled up its fermentation technology to produce palm oil alternatives with an annual output of over a thousand tons of the substitute.

A research team from Northwest University has decoded the lignin bolism blueprint of Pseudomonas bacteria transforming plant waste into energy.

A team from Beijing University of Chemical Technology has developed a -editing system to enhance the production of free fatty acids in Rhodosporidium toruloides.

Yali Biosynthesis of Mother's Milk Fat OPO is about to obtain FDA GRAS certification.

Jiangnan University has cracked the bolic bottleneck of vitamin K2 increasing its yield by 22.3%.

Amyris' former CEO is at the helm raising 130 million yuan. The startup is developing proprietary enzymes to double protein absorption rates.

Facing difficulties in fundraising and the collapse of partnerships a cultured meat startup has declared bankruptcy and is selling off its assets.

East China University of Science and Technology has developed a modular multi-enzyme cascade platform to synthesize 22 non-natural amino acids using glycerol as the raw material.

Nature highlights that AI has been used to efficiently design protein binders with a success rate approaching 50%.

South China Agricultural University has developed multi-colored glowing succulents that can emit light for up to 2 hours with a cost of only 10 yuan.

A Chinese scholar serving as both the first author and corresponding author published a paper in Cell developing a photo-genetic platform to screen for broad-spectrum antiviral drugs which have been proven effective against multiple viruses.

A South Korean team has developed an engineered Corynebacterium platform breaking through the gram-level barrier in lutein production.