Industry trends

A Chinese postdoctoral researcher as the first author the Nobel Prize-winning team utilized AI to design TCRs from scratch and is about to establish a company.

在精准免疫治疗需求日益增长的今天，如何高效、特异性地识别病变细胞，尤其是携带微弱病理信号的癌细胞和病毒感染细胞，成为制约 T 细胞疗法普及的关键瓶颈。细胞表面的 I 类主要组织相容性复合体（MHC-I）通过呈递内源性肽段实现免疫监视。当细胞感染病毒或发生癌变时，MHC-I 会展示疾病相关肽段形成 pMHC-I 复合物，成为 T 细胞受体（TCR）识别的靶标。然而，天然 TCR 对特定 pMHC 复

Two major companies under Flagship have laid off nearly a hundred people.

据外媒报道，波士顿知名风投机构 Flagship Pioneering 生态系统内两家重量级企业：Generate Biomedicines 与 Tessera Therapeutics 近期相继裁员。Generate Biomedicines 发言人周三通过邮件声明表示，公司已缩减 10% 的员工规模。值得注意的是，其研发负责人 Alexandra Snyder 本月已转投默沙东担任高级副总裁，

"Smart Bacteria" Conquer Kidney Stones! Stanford Team Repurposes Gut Bacteria to Precisely Degrade Oxalate in Urine

A team from Zhejiang University has launched a multimodal large language model that can design biomolecules d on human instructions.

Biodegradable and recyclable! Chen Zhaoji from Wuhan University and others have developed a "paper plastic" that can support a weight of 65 kg and degrade naturally in 180 days.

A team from Huazhong University of Science and Technology has developed a non-pathogenic bacteria-nanohybrid that works synergistically to inhibit tumors achieving a tumor targeting rate of 50%.

Chinese scholars turn food waste into treasure synthesizing 100% biodegradable bioplastic in two steps.

A team from the University of Pennsylvania used AI to decode animal venom discovering hundreds of potential antibiotics.